DNA Sequencing: How to Choose the Right Technology
WEBAug 6, 2021 · The global market for DNA sequencing is predicted to grow from $15.7 billion in 2021 to $37.7 billion by 2026. The rising prevalence of viral diseases, such as COVID-19, and the increasing cases of cancer globally are likely to drive genomic research and propel the industry at an even more rapid rate.
Sample Preparation for NGS – A Comprehensive Guide
WEBAug 21, 2024 · Step #3: Amplification. This is an optional step, but it is usually required. It is dependent on the application of NGS and the sample size. Amplification becomes essential to obtain enough coverage for reliable sequencing for samples with small amounts of starting material.
Long-read sequencing vs short-read sequencing
WEBJul 26, 2021 · Long-read sequencing. Long-read sequencing technologies are capable of reading longer lengths, between 5,000 and 30,000 base pairs. Therefore, they immediately address one of the main challenges faced by short-read sequencing. They sequence a single molecule, eliminating amplification bias, and …
Cancer Genomics ONLINE
WEBCancer Genomics ONLINE. When: April 15, 2021 Time: 3:00 pm. The webinar will be available on-demand after this date. REGISTER. The first cancer genome paper was published in 2008, and in just 13 years the power of sequencing and analytics has established genomics as an essential tool in our understanding and treatment of cancers.
What is multiplex PCR? - Front Line Genomics
WEBJul 26, 2021 · Multiplex PCR is a technique whereby PCR is used to amplify several different DNA sequences simultaneously. It is a type of target enrichment approach. It was first described in 1988 as a method to detect deletion mutations in the dystrophin gene – the largest known human gene. The dystrophin complex connects the …
A guide to proteomics - Front Line Genomics
WEBAug 27, 2021 · A guide to proteomics. The term ‘proteomics’ was first coined in 1996 by Marc Wilkins, used to define the large-scale analysis of all the proteins in a cell, tissue or organism. The goal of proteomics was to obtain a more wholesome view of biology, as opposed to studying each protein individually. Proteomics has …
A brief history of Next Generation Sequencing (NGS)
WEBJul 26, 2021 · 2000: Lynx Therapeutics Company launched the first of the NGS technologies, called Massively parallel signature sequencing (MPSS). The company was later bought by Illumina. 2004: 454 Life Sciences marketed a new generation pyrosequencing technology, called the Roche GS20. It …
WEBCONTENTS 28 1 INTRODUCTION 3 ABBREVIATIONS 4 GLOSSARY 6 CHAPTER 1: THE TECHNOLOGY OF GENE EDITING Over the last few decades, researchers have identified a number of different techniques and tools that …
AlphaFold 2 open up protein structure prediction software for all
WEBJul 16, 2021 · AlphaFold 2. DeepMind has now released the source code for the newest version of AlphaFold, which is freely accessible in Nature. AlphaFold is an attention-based neural network system that predicts protein 3D structures from their amino acid sequences. It aligns a protein’s amino acid sequence with evolutionarily related sequences to estimate ...
AP1G1: The new gene being linked to certain neurodevelopmental ...
WEBImmy Mobley 24 June 2021. Researchers have discovered that the gene AP1G1 could be associated with certain neurodevelopmental disorders and intellectual disabilities. A person with an intellectual disability is an individual who experiences certain limitations in terms of cognitive functioning. It is estimated that 3% of the global population ...