Villefranche-sur-Saône is a commune in the Rhône department in eastern France. It lies 1 mile west of the river Saône, and is around 25 kilome…Villefranche-sur-Saône is a commune in the Rhône department in eastern France. It lies 1 mile west of the river Saône, and is around 25 kilometres north of Lyon. The inhabitants of the town are called Caladois.