Using CRISPR-Cas9, the scientists introduced the corresponding mouse mutation, V1613M, into both copies of the mouse gene.

As immature egg cells, called oocytes get older, they begin having problems with cell division. This can result in aneuploidy ...

New research has uncovered a series of mutations in the SARS-CoV-2 spike protein that enhanced the virus' ability to infect the brains of mice. The findings may help scientists understand its ...

The accumulation of mutations in DNA is often mentioned as an explanation for the aging process, but it remains just one ...

The latest, highly contagious subvariants are driving infections, but new vaccines may help stem the tide of another wave — ...

Their studies showed that when cancerous mutations occurred during the regenerative period, the mice were more likely to develop early-stage intestinal tumors. “Having more stem cell activity is ...

MIT researchers report that fasting aids in the regeneration and healing of intestinal stem cells in mice, but also increases ...

A laboratory in Tel Aviv has become the legacy of Marisol O’Brien’s all too short life in Boston.

A common diabetes medication, metformin, slows the growth of precancerous cells in the oesophagus while some metabolic ...

Mission Bio explains how single-cell multiomics can help researchers overcome the challenges of heterogeneous editing ...

Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...

In the lung, the spike protein looked very similar to the virus used to infect the mice. In the brain, however, most viruses had a deletion or mutation in a critical region of spike that dictates ...